Nanotube bottoms are uniformly etched to produce consistent nanoscale pores.

Current Treatment Challenges

Even the best treatments don’t work if patients don’t take them

Pressure from payers for improved adherence is driving the need to innovate novel solutions in drug delivery; with only 61.4% of patients actually taking their medication 1 , non-adherence costs the United States, alone, more than $100B annually 2. In addition to the pain and compliance issues associated with injections and infusions, the delivery profile is often non-optimal, negatively affecting treatment outcomes. Oral delivery via pills does not have the pain associated with injections and infusions, yet still suffers from poor adherence. Extended release implants address all of these issues head on, and likely improve patient outcomes.

Nano Precision Medical is developing a biocompatible, miniaturized,, subdermal implant with the NanoPortal TM membrane to provide long-term, substantially constant-rate delivery of therapeutic macromolecules for up to a year.

1 Kongkeaw, 2017
2 IMS Institute for Healthcare Informatics, 2013

Pain, No Gain

Current Standard Therapy

Technology injection delivery limitations current standard delivery

  • Difficulty with adherence

    Frequent, uncomfortable treatments lead to reduced patient compliance and suboptimal outcomes.

  • Lack of efficacy

    Diminished concentrations between treatments can limit treatment efficacy.

  • Unnecessary side effects

    Spikes in concentration immediately following treatments often cause toxicity and undesirable patient side effects.

Worry-Free, Constant-Rate Delivery

NanoPortal Eliminates the Need for Frequent Administration

Technology injection delivery limitations nanoportal delivery

  • Guaranteed adherence

    Clinicians and insurance providers can trust that patients receive their prescribed treatment, maximizing the chance for positive outcomes.

  • Constant-rate release

    Consistent delivery rates eliminate concentration spikes and diminished concentrations, overcoming the pharmacokinetic inadequacies of standard therapy.

  • Extended duration

    Patients can be confident that they will receive their medication for many months without any need for continual oversight.

The NanoPortal TM Solution

Nano Precision Medical is developing a small, miniturized implant with the NanoPortal membrane to provide long-term, constant-rate delivery of therapeutics for many months. The rice-grain sized device is designed for easy implantation under the skin.

Nanoportal solution

  • Easy to implant

    Our miniturized device can be implanted in minutes during a simple, outpatient procedure.

  • Potent formulation

    Our potent formulation permits an extended duration of therapy to fit into a compact device.

  • Nano-enabled

    Biocompatible, titania, nanoporous membrane technology enables constant-rate release without moving parts or electronics.

The Goldilocks Effect